Table 3 Diagnostic performance of AAT-A3F and other biomarkers for predicting NASH.

From: Tri-antennary tri-sialylated mono-fucosylated glycan of alpha-1 antitrypsin as a non-invasive biomarker for non-alcoholic steatohepatitis: a novel glycobiomarker for non-alcoholic steatohepatitis

 

AUC

Cut-off

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

AAT-A3F

0.687

14.1

38

95

90

54

cCK18

0.655

977

42

86

79

53

M2BPGi

0.749

0.69

77

69

77

69

FIB4 index

0.700

1.44

73

67

74

66

APRI

0.672

0.86

50

81

77

55

  1. Abbreviations: AUC, area under the curve; NPV, negative predictive value; PPV, positive predictive value; NASH: non-alcoholic steatohepatitis
Back to article page