Table 4 Diagnostic performance of AAT-A3F and other biomarkers for predicting early NASH (Brunt stage S0-1).

From: Tri-antennary tri-sialylated mono-fucosylated glycan of alpha-1 antitrypsin as a non-invasive biomarker for non-alcoholic steatohepatitis: a novel glycobiomarker for non-alcoholic steatohepatitis

 

AUC

Cut-off

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

AAT-A3F

0.696

7.9

79

58

56

80

cCK18

0.665

977

49

86

70

71

M2BPGi

0.673

0.79

55

80

66

72

FIB4 index

0.624

1.44

64

67

57

73

APRI

0.648

0.86

51

81

65

71

  1. Abbreviations: AUC, area under the curve; NPV, negative predictive value; PPV, positive predictive value; NASH: non-alcoholic steatohepatitis.
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