Figure 1 | Scientific Reports

Figure 1

From: An inhibitor of apoptosis protein (EsIAP1) from Chinese mitten crab Eriocheir sinensis regulates apoptosis through inhibiting the activity of EsCaspase-3/7-1

Figure 1

The sequence characteristics and phylogeny of EsIAP1. (a) The predicted structural domain of EsIAP1, which contains two BIR domains. (b) Multi-sequence alignment the amino acids sequences of BIR1 and BIR2 domains among IAP family members. The species and the GenBank accession numbers are as follows: Homo sapiens c-IAP1 (Q13490.2), Mus musculus c-IAP1 (Q62210.1), H. sapiens c-IAP2 (Q13489.2), M. musculus c-IAP2 (O08863.2), M. musculus XIAP (AAB58376.1), H. sapiens XIAP (AAC50373.1), Litopenaeus vannamei IAP1 (ADH03018.1), Bombyx mori IAP (NP_001037024), Penaeus monodon IAP (NP_001037024.), Crassostrea gigas IAP1 (AEB54799.1), and Drosophila melanogaster DIAP2 (Q24307.3). Conserved cysteine and histidine residues of EsIAP1 are marked with “▼”. Other conserved, but not consensus amino acids are shaded in gray. (c) The unrooted tree was built based on the amino acid sequences of 13 IAP family members. The species and the GenBank accession numbers were as follows: H. sapiens c-IAP1 (Q13490.2), M. musculus c-IAP1 (Q62210.1), H. sapiens c-IAP2 (Q13489.2), M. musculus c-IAP2 (O08863.2), M. musculus XIAP (AAB58376.1), H. sapiens XIAP (AAC50373.1), L. vannamei IAP1 (ADH03018.1), L. vannamei IAP2 (ADY38394.1), P. monodon IAP (ABO38431.1), Danio rerio XIAP (AAI33127.1), B. mori IAP (NP_001037024), D. melanogaster DIAP1 (Q24306.2) and E. sinensis IAP1 (AWK27045).

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