Table 1 Baseline characteristics of the subcohort and renal cell carcinoma (RCC) and clear cell renal cell carcinoma (ccRCC) cases; Netherlands Cohort Study on diet and cancer, 1986–2006.

From: Germline polymorphisms in the Von Hippel-Lindau and Hypoxia-inducible factor 1-alpha genes, gene-environment and gene-gene interactions and renal cell cancer

Baseline characteristics (mean (SD))

Subcohort members

RCC

ccRCC

Total (n)

3004

406

263

Age (y)

61.3 (4.2)

60.7 (3.9)

60.6 (3.9)

Male sex (%)

49.6

65.8

64.3

Tumor stage (%)a

   

Stage 1/2

—

49.8

51.0

Stage 3/4

—

38.2

39.5

Undefined

—

12.1

9.5

Cigarette smoking status (%)

   

Never smoker

36.8

26.9

26.6

Former smoker

36.4

43.8

45.3

Current smoker

26.9

29.3

28.1

Smoking intensity (cig/d)b

15.2 (10.2)

17.0 (11.7)

16.2 (10.5)

Smoking duration (y)b

31.5 (12.2)

32.0 (11.6)

31.4 (11.3)

Hypertension (%)

26.4

33.5

33.5

BMI (kg/m2)

25.0 (3.1)

25.4 (3.0)

25.5 (2.9)

Alcohol consumption (g ethanol/d)c

13.7 (15.0)

15.4 (15.3)

14.9 (14.7)

Energy intake (kcal)

1915 (505)

1998 (529)

1994 (517)

Diuretic medication (%)

11.0

14.0

15.2

Antihypertensive medication (%)

20.5

24.6

26.2

  1. The subcohort includes 15 RCC cases, of which 11 ccRCC cases. Solely participants with complete information for main exposures are included in this table. SD = Standard deviation, RCC = renal cell carcinoma, ccRCC = clear cell renal cell carcinoma, BMI = Body Mass Index.
  2. aAccording to the TNM version used at time of diagnosis by the Netherlands Cancer registry.
  3. bIn former and current smokers only.
  4. cIn alcohol consumers only.
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