Table 1 Demographic characteristics of the study participants.

From: Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population

 

Discovery Cohort (mean ± SD)

Replication Cohort (mean ± SD)

p-values for differences between Discovery and Replication cohorts

Sex, Male:Female

667:686

673:503

7.96E-05

Age, years ± SD

47 ± 13.8

47 ± 10.7

0.97

Weight, Kg ± SD

88.5 ± 21.1

92.4 ± 17

3.62E-06

Height, cm ± SD

165 ± 9.6

166.5 ± 8.9

0.006

BMI, Kg/m2 ± SD

32.4 ± 7.4

31.2 ± 5.7

6.15E-06

WC, cm ± SD

102.2 ± 16.4

100.5 ± 12.1

0.003

LDL, mmol/L ± SD

3.1 ± 0.97

3.4 ± 0.9

<2.2E-16

HDL, mmol/L ± SD

1.1 ± 0.4

1.1 ± 0.3

0.82

TC, mmol/L ± SD

4.9 ± 1.1

5.2 ± 1.0

7.77E-12

TG, mmol/L ± SD

1.7 ± 1.2

1.6 ± 1.0

0.002

HbA1c, mmol/L ± SD

7.1 ± 2.1

6.0 ± 1.4

<2.2E-16

FPG, mmol/L ± SD

7.3 ± 3.6

5.9 ± 2.3

<2.2E-16

SBP, mmHg ± SD

128 ± 17.5

129.1 ± 16.7

0.06

DBP, mmHg ± SD

77.9 ± 10.6

78.7 ± 11.1

0.035

Proportion of the participants that are obese@ (BMI ≥ 30 Kg/m2)

59.3%

45.5%

7.43E-05

Proportion of the participants that are diabetic

44.7%

38.4%

0.002

Proportion of the participants that are hypertensive

44.9%

35.7%

3.61E-06

Proportion of the participants that consume lipid lowering medication

9.8%

0.3%

<2.2E-16

Proportion of the participants that consume glucose lowering medication

16.0%

4.6%

<2.2E-16

Proportion of the participants that consume blood pressure medication

11.9%

7.2%

0.0

  1. Abbreviations: WC, waist circumference; TC, total cholesterol; HbA1c, glycated hemoglobin; FPG, fasting plasma glucose; SBP, systolic blood pressure; DBP, diastolic blood pressure; SD, standard deviation.
  2. @The distribution of the participants onto normal weight (BMI 20 to <25): overweight (BMI 25 to <30): obese (BMI 30 to <40): morbid obese (BMI ≥ = 40) = 222:328:597:206 in the discovery cohort; and 93:442:559:82 in the replication cohort.
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