Table 1 Marker Genes for Type I and Type IIa muscle fibers.

From: Single-cell transcriptional profiles in human skeletal muscle

Marker Genes

Type I (LFC)

Type IIa (LFC)

Sarcomeric

TPM3 (3.68)

TNNC1 (3.35)

TNNI1 (3.24)

TNNT1 (3.47)

MYH7 (3.19)

MYL2 (3.29)

MYL3 (3.50)

MYL6B (2.71)

ANKRD2 (1.30)

MYOZ2 (3.18)

TPM1 (3.363)

TNNC2 (2.86)

TNNI2 (3.43)

TNNT3 (3.81)

MYH2 (3.67)

MYH1 (1.72)

MYL1 (1.59)

MYLPF (3.14)

MYBPC2 (3.11)

ENO3 (1.67)

Calcium transport

ATP2A2 (3.12)

CASQ2 (1.86)

PLN (0.96)

ATP2A1 (2.65)

SLN (1.56)

Metabolism

CD36 (1.14)

CYB5R1 (1.34)

FABP3 (1.11)

LDHB (2.59)

ALDOA (1.73)

GAPDH (1.32)

LDHA (1.57)

PKM (1.31)

PFKM (1.45)

PGM1 (1.03)

General

CA3 (1.18)

MYL12A (1.32)

PDLIM1 (2.59)

DDIT4L (0.97)

G0S2 (1.05)

  1. Log2 fold-change vs. the opposite muscle fiber-type is in parentheses after each gene name. Italicized genes have not been previously identified as fiber-type specific, to the best of our knowledge.
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