Table 3 Hazard ratios of the risk of AF, univariable and multivariable adjusted.

From: Atrial fibrillation is associated with lean body mass in postmenopausal women

Factors

Univariable

Model 1*

Model 2**

VIF***

HR (95% CI); p-value

c-stat; [n,cases]

HR (95% CI); p-value

c-stat; [n,cases]

HR (95% CI); p-value

c-stat; [n,cases]

BMI, kg/m2

normal weight

ref

0.52; [5496, 812]

ref

0.67; [5496, 812]

ref

0.69; [5124, 757]

ref

overweight

1.00 (0.86–1.17); 0.996

1.01 (0.87–1.18); 0.870

0.99 (0.84–1.16); 0.898

3.61

obese

1.33 (1.10–1.60); 0.003

1.44 (1.20–1.74); <0.001

1.27 (1.03–1.55); 0.023

5.28

Weight, kg

T1

ref

0.53; [5496, 812]

ref

0.68; [5496, 812]

ref

0.69; [5124, 757]

ref

T2

1.01 (0.85–1.21); 0.872

1.12 (0.94–1.34); 0.194

1.13 (0.94–1.35); 0.204

3.45

T3

1.24 (1.05–1.46); 0.012

1.54 (1.30–1.83); <0.001

1.44 (1.21–1.73); <0.001

8.92

Height, m

T1

ref

0.52; [5496, 812]

ref

0.68; [5496, 812]

ref

0.69; [5124, 757]

ref

T2

0.89 (0.75–1.06); 0.188

1.09 (0.92–1.30); 0.315

1.07 (0.89–1.29); 0.454

1.82

T3

1.05 (0.89–1.24); 0.538

1.52 (1.28–1.81); <0.001

1.53 (1.28–1.83); <0.001

3.05

Total fat mass, kg

T1

ref

0.53; [5172, 760]

ref

0.67; [5172, 760]

ref

0.69; [5134, 760]

ref

T2

0.95 (0.79–1.14); 0.570

0.99 (0.83–1.19); 0.950

1.00 (0.83–1.20); 0.994

5.03

T3

1.17 (0.98–1.39); 0.078

1.30 (1.09–1.54); 0.003

1.23 (1.03–1.47); 0.021

3.05

Fat %

T1

ref

0.52; [5172, 760]

ref

0.67; [5172, 760]

ref

0.69; [5134, 760]

ref

T2

1.11 (0.93–1.33); 0.245

1.12 (0.93–1.33); 0.228

1.12 (0.94–1.34); 0.210

3.59

T3

1.17 (0.99–1.40); 0.073

1.23 (1.03–1.47); 0.022

1.16 (0.97–1.39); 0.107

7.24

Total lean mass, kg

T1

ref

0.52; [5172, 760]

ref

0.68; [5172, 760]

ref

0.69; [5134, 760]

ref

T2

1.13 (0.94–1.35); 0.185

1.26 (1.06–1.51); 0.011

1.26 (1.05–1.51); 0.011

2.45

T3

1.19 (1.00–1.43); 0.048

1.55 (1.30–1.85); <0.001

1.51 (1.26–1.81); <0.001

5.19

LBMi, kg/m2

T1

ref

0.52; [5157, 757]

ref

0.67; [5157, 757]

ref

0.69; [5119, 757]

ref

T2

1.18 (0.99–1.41); 0.066

1.16 (0.97–1.39); 0.100

1.15 (0.96–1.37); 0.135

2.04

T3

1.20 (1.01–1.44); 0.042

1.21 (1.01–1.44); 0.037

1.15 (0.96–1.38); 0.130

4.03

  1. The anthropometric (BMI, height and weight) and DXA scan derived body composition measures (Total fat mass, fat %, total lean mass and LBMi) have been analysed individually, not adjusted for each other.
  2. *Variables adjusted for: age.
  3. **Variables adjusted for: age, alcohol, smoking, education, exercise, HRT, hypertension, hyperlipidaemia, diabetes, IHD, PAD, CHF, thyroid disease and scanner model.
  4. ***With all variables of model 2, all anthropometric and body composition measures. All variables adjusted for and had a VIF < 2.5.
  5. HR, Hazard ratios; 95% CI, 95% confidence intervals; c-stat, c-statistics; ref, reference; fat %, total percentage of body fat; LBMi, Lean Body Mass index.
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