Table 2 Kinetic parameters of log-linear and Weibull models for B. atrophaeus endospores subjected under thermal inactivation and ultraviolet inactivation on surfaces, B. subtilis endospores subjected under oxygen plasma inactivation, and G. stearothermophilus endospores challenged with vaporized hydrogen peroxide. All the time parameters were displayed in min. All data were represented as means ± standard deviation of the mean. The mean data were analyzed by Student’s t test. The level of significance was considered at p < 0.05. Goodness-of-fit of the models was validated by R2 values.

From: Quantitative and Fast Sterility Assurance Testing of Surfaces by Enumeration of Germinable Endospores

Inactivation

EGA

Culture

Linear

Weibull

Linear

Weibull

D

R2

α

β

tc

R2

D

R2

α

β

tc

R2

Dry heat

25.6 ± 3.2

0.93

15.4 ± 1.7

1.55 ± 0.2

14.7 ± 2.1

0.97

3.4 ± 0.6

0.95

2.8 ± 0.2

0.65 ± 0.1

2.6 ± 0.3

0.98

Dry UV

12.4 ± 4.5

0.80

7.7 ± 0.4

2.29 ± 0.5

6.9 ± 0.5

0.97

11.6 ± 3.8

0.90

6.8 ± 0.5

0.88 ± 0.1

6.1 ± 0.3

0.9

O2 plasma

14.0 ± 1.6

0.99

14.4 ± 1.0

1.02 ± 0.1

14.2 ± 1.2

0.99

16.9 ± 4.0

0.99

17.5 ± 2.2

1.01 ± 0.1

17.2 ± 2.3

0.99