Figure 2
From: Prenatal Testosterone Exposure Disrupts Insulin Secretion And Promotes Insulin Resistance

Mean ± SEM glucose concentrations (A,B) and insulin concentrations ((C,D)) during and the first 20 minutes after intravenous glucose tolerance test (IVGTT), respectively, in control female sheep (C-females, open circles, n = 6) and prenatally exposed to testosterone female sheep (T-females, closed circles, n = 6) before (A,C) and after (B,D) an acute injection of 40 mg of testosterone. Time 0 represents the mean of basal concentrations at -15, -10 and 0 min before glucose infusion. *P < 0.05 denotes difference between C- and T-females at a given time point after glucose infusion. Different letter indicates significant difference within a same group either with or without the acute testosterone treatment.