Table 2 Summary of testosterone plasma concentrations (ng/ml) in pregnant sheep and ovariectomized sheep during testosterone treatments.

From: Prenatal Testosterone Exposure Disrupts Insulin Secretion And Promotes Insulin Resistance

 

C-females (n = 6)

T-females (n = 6)

Mothersa

ND

2.41 ± 0.94*

Females pre Tb

ND

ND

Females post Tb

1.71 ± 0.22

1.72 ± 0.27

  1. *Difference (P < 0.05) between groups within a sample time.
  2. a,b Difference (P < 0.05) between groups in presence or absence of acute testosterone treatment.
  3. aMothers corresponded to pregnant sheep (T-treated) with intramuscular injections of testosterone propionate 30 mg twice per week from day 30 to 90 and 40 mg twice per week from day 91 to 120 of pregnancy. Control dams received the vehicle of the hormone during the same time intervals.
  4. bCorrespond to control females (C-females) and prenatally exposed to T females (T-females) treated with an acute testosterone injection 48 hours prior to an intravenous glucose tolerance test.
  5. *Difference between groups (P < 0.05).
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