Figure 4
From: Recombinant thrombomodulin prevents acute lung injury induced by renal ischemia-reperfusion injury

Vascular permeability in the lungs and kidneys after bilateral renal IR. EBD contents were determined in the lung and kidney at 24 h after bilateral renal IR. The mice were pretreated with saline (IR group) or 10 mg/kg of rTM (IR + rTM group). n = 4 in sham group; n = 6 in IR and IR + rTM groups. *P < 0.05 versus respective control. Abbreviations: EBD, Evans blue dye; IR, ischemia-reperfusion; rTM, recombinant thrombomodulin.