Figure 8
From: Recombinant thrombomodulin prevents acute lung injury induced by renal ischemia-reperfusion injury

Plasma HMGB1 levels in mice after renal IR. The plasma levels of HMGB1 were measured at 6 h and 24 h after bilateral renal IR. The mice were pretreated with saline (IR group) or 10 mg/kg of rTM (IR + rTM group). n = 6 per group. *P < 0.05 versus respective control. Abbreviations: HMGB1, high morbidity group box-1; IR, ischemia-reperfusion; rTM, recombinant thrombomodulin.