Figure 2 | Scientific Reports

Figure 2

From: In silico study of the effects of anti-arrhythmic drug treatment on sinoatrial node function for patients with atrial fibrillation

Figure 2

Action potentials (Vm) and the heart rate of the human sinoatrial node (SAN) cell. (A,B) Comparison of action potentials (Vm) and maximum rate of rise of membrane potential ((dV/dt)max) between normal and SND conditions. (C) AF-induced electrophysiological remodelling slowed the heart rate. (D) Simulated results are compared with the clinical findings (Barra et al.64, Mun et al.17, Chang et al.65, Hocini et al.66, Chen et al.67 and Killu et al.68) in patients with SND after catheter ablation of AF.

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