Table 2 Univariable and Multivariable Cox model of prognostic factors for recurrence-free survival and overall survival.

From: Prognostic impact of PD-L1 expression in correlation with neutrophil-to-lymphocyte ratio in squamous cell carcinoma of the lung

 

Recurrence-free survival

Overall survival

Univariable analysis

Multivariable analysis

Univariable analysis

Multivariable analysis

HR

95% CI

P-

HR

95% CI

P-

HR

95%CI

P-

HR

95%CI

P-

Age (per 1-year increase)

1.016

0.972–1.063

0.476

   

1.031

0.981–1.083

0.229

   

Sex, female (vs male)

0.791

0.307–2.037

0.791

   

0.777

0.272–2.218

0.637

   

Smoking status, current smoker (vs never smoker)

1.049

0.543–2.027

0.887

   

1.058

0.526–2.129

0.874

   

Pathologic stage IB (vs IA)

0.940

0.488–1.814

0.855

   

1.040

0.518–2.089

0.911

   

Mode of lung resection, sub-lobar resection (vs lobectomy)

1.967

0.936–4.134

0.074

   

1.456

0.622–3.405

0.386

   

Adjuvant chemotherapy, performed

(vs not performed)

0.397

0.121–1.299

0.127

   

0.450

0.137–1.483

0.189

   

NLR-low/PD-L1(-) vs others

PD-L1(-): TPS = 0

0.237

0.083–0.674

0.007

0.239

0.082–0.693

0.008

0.260

0.091–0.745

0.012

0.276

0.094–0.808

0.019

PD-L1(-): TPS, 0–4

0.358

0.155–0.827

0.016

0.365

0.154–0.855

0.022

0.401

0.171–0.940

0.036

0.426

0.178–0.969

0.045

PD-L1(-): TPS, 0–9

0.396

0.179–0.878

0.023

0.392

0.173–0.888

0.025

0.378

0.161–0.883

0.025

0.390

0.164–0.928

0.033

PD-L1(-): TPS, 0–49

0.430

0.206–0.899

0.025

0.437

0.206–0.929

0.031

0.349

0.156–0.784

0.011

0.359

0.157–0.821

0.015

  1. HR, hazard ratio; CI, confidence interval.
  2. NLR, neutrophil-to-lymphocyte ratio.
  3. TPS, tumor proportion score.