Figure 3 | Scientific Reports

Figure 3

From: Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes

Figure 3

Localization of CTSB in the adipocyte fraction of obese WAT. (A) Representative images of WAT sections from ND and 8HFD mice immunostained for PLIN1, CTSB and F4/80. Scale bars represent 50 μm (upper and middle panels) and 10 μm (lower panels). Arrow indicates the co-localization between CTSB and F4/80, and arrowheads indicate the co-localization between CTSB and adipocytes. (B) qRT-PCR analysis for Ctsb mRNA levels in the adipocyte enriched fraction (AEF) and stromal vascular fraction (SVF) obtained from the WAT of ND and 8HFD groups. Values indicate the mean ± SD. Differences between values were analysed by Tukey-Kramer method with *P < 0.05, **P < 0.01 (n = 4).

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