Figure 2 | Scientific Reports

Figure 2

From: Liquid-like droplet formation by tumor suppressor p53 induced by multivalent electrostatic interactions between two disordered domains

Figure 2

Deletion of the disordered domains hindered p53 droplet formation. The 2D plots representing droplet formation of the NTCoreTet (a), CoreTetCT (b), and TetCT mutants (c) at different pHs and salt concentrations. The size and color of the circles represent OD350 and the average circularity of the droplets, respectively. The concentration of each mutant was 12 μM. In the primary structure of mutants presented at the top of each plot, rectangles and lines denote folded and disordered domains, respectively. The shaded regions in the primary structures are the deleted domains.

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