Table 3 Hazard ratios of dementia and Alzheimer’s dementia (AD) conversion according to cognitive profile.

From: Frontal-executive dysfunction affects dementia conversion in patients with amnestic mild cognitive impairment

 

Hazard ratio of demnetia conversion (CI 0.95)

P value

Hazard ratio of AD conversion

(CI 0.95)

P value

1M-MCI

REF

 

REF

 

2-domain MCI

1.59 (1.08–2.33)

0.019

1.57 (1.05–2.35)

0.027

    2MV-MCI

1.17 (0.60–2.26)

0.650

1.13 (0.57–2.26)

0.726

    2ML-MCI

1.44 (0.84–2.46)

0.188

1.46 (0.84–2.54)

0.182

    2MF-MCI

2.02 (1.29–3.16)

0.002

1.97 (1.23–3.14)

0.005

3-domain MCI

2.06 (1.36–3.13)

0.001

2.08 (1.35–3.21)

0.001

    3MLV-MCI

1.74 (0.81–3.72)

0.156

1.88 (0.87–4.06)

0.106

    3MLF-MCI

2.22 (1.38–3.57)

0.001

2.22 (1.35–3.63)

0.002

    3MVF-MCI

2.75 (1.47–5.16)

0.002

2.76 (1.44–5.31)

0.002

4-domain MCI

2.93 (1.74–4.94)

0.000

2.19 (1.20–3.96)

0.010

  1. Cox proportional hazard ratio of each aMCI subgroup was analyzed, compared to that of 1M-MCI group after controlling age, education year, diabetes and dyslipidemia. (confidence interval = 0.95).
  2. CI = confidence interval; 1M-MCI = single amnestic mild cognitive impairment; 2ML-MCI = amnestic MCI with memory and language dysfunction; 2MV-MCI = amnestic MCI with memory and visuospatial dysfuction; 2MF-MCI = amnestic MCI with memory and frontal-executive dysfunction; 3MLV-MCI = amnestic MCI with memory, language, and visuospatial dysfunction; 3MLF-MCI = amnestic MCI with memory, language, and frontal-executive dysfunction; 3MVF-MCI = amnestic MCI with memory, visuospatial, and frontal-executive dysfunction; 4MLVF-MCI = amnestic MCI with memory, language, visuospatial, and frontal-executive dysfunction.
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