Figure 4
From: Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats
Comparison of metabolites between omeprazole-treated and control Wistar rats. Rats were sacrificed at the end of the experiment (day 30) and serum and stool were collected. The serum and stool metabolites were analyzed by GC-TOFMS. (a) Heatmap showing the abundance of the identified metabolites (b) Statistical comparison between treated and control rats was performed with exact Wilcoxon-Mann-Whitney test at α = 0.05. Three and five metabolites were found to show significant differences in serum and stool samples respectively.
