Table 4 Neurocognitive outcomes among adult survivors of childhood ALL compared to national norms.
Neurocognitive test | Mean (95% CL) | FDR p-value |
|---|---|---|
Intelligence | ||
Verbal ability | −0.65 (−0.90, −0.4,) | <0.001 |
Perceptual ability | −0.04 (−0.23, 0.16) | 0.79 |
Processing speed | ||
Dominant motor speed | −0.76 (−0.96, −0.53) | <0.001 |
Non-dominant motor speed | −0.78 (−1.0, −0.53) | <0.001 |
Visual-motor speed | −0.39 (−0.56, −0.23) | <0.001 |
Visual speed | −0.20 (−0.39, −0.00) | 0.10 |
Processing speed | −0.36 (−0.56, −0.17) | 0.001 |
Reaction time | 0.21 (−0.03, 0.44) | 0.17 |
Executive Function | ||
Cognitive flexibility | −0.79 (−1.10, −0.48) | <0.001 |
Working memory | −0.48 (−0.68, −0.27) | <0.001 |
Attention | ||
Focused attention | −0.14 (−0.39, 0.12) | 0.43 |
Omissions | −0.05 (−0.32, 0.23) | 0.79 |
Commissions | −0.10 (−0.34, 0.14) | 0.50 |
Variability | −0.11 (−0.36, 0.14) | 0.50 |
Detectability | −0.087 (−0.30, 0.12) | 0.50 |
Memory | ||
Memory span | −0.57 (−0.79, −0.35) | <0.001 |
New learning | −0.16 (−0.41, 0.085) | 0.31 |
Short-term recall | 0.00 (−0.23, 0.23) | 1.00 |
Long-term recall | −0.066 (−0.30, 0.17) | 0.68 |
Academics | ||
Reading | −0.44 (−0.54, −0.34) | <0.001 |
Math | −0.73 (−0.92, −0.54) | <0.001 |
BRIEF Self-Reporta | ||
Inhibitory control | 0.12 (−0.07, 0.32) | 0.32 |
Behavioral flexibility | 0.40 (0.16, 0.63) | 0.003 |
Self-monitoring | −0.025 (−0.25, 0.20) | 0.85 |
Self-initiation | 0.14 (−0.071, 0.36) | 0.31 |
Working memory | 0.90 (0.64, 1.16) | <0.001 |
Planning | 0.15 (−0.067, 0.37) | 0.31 |
Task completion | 0.22 (0.003, 0.43) | 0.10 |
Organization | 0.075 (−0.105, 0.26) | 0.50 |
