Table 3 Risk factors for co-prevalent active tuberculosis among 116,742 contacts of tuberculosis cases in congregate settings.

From: Risk of active tuberculosis development in contacts exposed to infectious tuberculosis in congregate settings in Korea

 

Contacts Without

Contacts With

Unadjusted

Adjusted

Co-prevalent TB, No. (%)

Co-prevalent TBa, No. (%)

Odds Ratio (95% CI)

p–value

Odds Ratio (95% CI)

p–value

Total

116,623

119

  

Index factors

Sex

Male

70,744

(99.9)

83

(0.1)

1.49 (1.01–2.21)

0.044

1.56 (1.05–2.33)

0.026

Female

45,879

(99.9)

36

(0.1)

Reference

 

Reference

 

Age, years

0–18

41,007

(99.9)

26

(0.1)

Reference

   

19–35

36,147

(99.9)

36

(0.1)

1.57 (0.94–2.60)

0.079

  

36–64

23,815

(99.8)

37

(0.2)

2.45 (1.48–4.04)

0.000

  

≥65

15,654

(99.9)

20

(0.1)

2.01 (1.12–3.61)

0.019

  

Sputum smear status

Smear-positive

62,265

(99.9)

89

(0.1)

2.75 (1.80–4.21)

0.000

2.29 (1.45–3.59)

0.000

Smear-negative

53,999

(99.9)

28

(0.1)

Reference

 

Reference

 

Unknown

359

(99.4)

2

(0.6)

10.74 (2.55–45.27)

0.001

6.80 (1.59–29.12)

0.010

Cavities on chest radiograph

Cavities

29,264

(99.9)

43

(0.1)

1.67 (1.14–2.44)

0.008

  

No Cavities

80,966

(99.9)

71

(0.1)

Reference

   

Unknown

6,393

(99.9)

5

(0.1)

0.89 (0.36–2.21)

0.805

  

Contact factors

Sex

Male

62,402

(99.9)

70

(0.1)

1.24 (0.86–1.78)

0.246

  

Female

54,221

(99.9)

49

(0.1)

Reference

   

Age, years

0–18

45,103

(99.9)

30

(0.1)

Reference

   

19–35

34,087

(99.9)

30

(0.1)

1.32 (0.79–2.19)

0.278

  

36–64

29,183

(99.9)

40

(0.1)

2.06 (1.28–3.30)

0.003

  

≥65

8,250

(99.8)

19

(0.2)

3.46 (1.94–6.15)

0.000

  

Congregate settings

Schools

65,740

(99.9)

41

(0.1)

Reference

 

Reference

 

Workplaces

14,313

(99.8)

23

(0.2)

2.57 (1.54–4.29)

0.000

1.66 (0.96–2.85)

0.067

Healthcare facilities

18,364

(99.8)

36

(0.2)

3.14 (2.00–4.92)

0.000

2.56 (1.62–4.06)

0.000

Social welfare facilities

9,779

(99.9)

12

(0.1)

1.96 (1.03–3.74)

0.039

1.69 (0.88–3.26)

0.113

Others

8,427

(99.9)

7

(0.1)

1.33 (0.59–2.97)

0.483

1.09 (0.48–2.44)

0.829

Type of contact

Close contact

51,225

(99.9)

61

(0.1)

1.40 (0.97–2.02)

0.073

  

Casual contact

62,375

(99.9)

53

(0.1)

Reference

   

Unknown

3,023

(99.8)

5

(0.2)

1.94 (0.77–4.87)

0.155

  
  1. TB, tuberculosis; CI, confidence interval.
  2. aContact diagnosed within 90 days after diagnosis of the index patient.