Figure 3
From: Imbalance in B cell and T Follicular Helper Cell Subsets in Pulmonary Sarcoidosis
Increased relative number of CD5 + CD27− and decreased number of CD27+ memory B cells in patients with sarcoidosis. Representative flow cytometry dot plots showing expression of CD5 vs. CD27 in a sarcoidosis patient (a) and healthy control subject (b). Scatter plots C showing the percentages of CD5 + CD27− cell among total B cell population, respectively, in the peripheral blood samples for sarcoidosis patients (n = 37, black circles, SP) and healthy control subjects (n = 35, white circles, HC). Each dot represents individual subjects, and horizontal bars represent the group medians and quartile ranges (Med (Q25; Q75). Statistical analysis was performed with the Mann-Whitney U test. (*** – p < 0.001).
