Table 5 Meta-analysis of the association between LTA rs909253 A/G polymorphisms and ankylosing spondylitis risk.

From: Associations of lymphotoxin-a (LTA) rs909253 A/G gene polymorphism, plasma level and risk of ankylosing spondylitis in a Chinese Han population

SNP

Comparison

Category

Category

OR (95% CI)

P-value

P for heterogeneity

LTA rs909253

G vs. A

Total

 

1.20(0.70, 2.07)

0.512

0.000

  

2019

This study

0.70(0.53, 0.94)

0.016

NA

  

2017

Jia B

1.53(1.07, 2.18)

0.020

NA

  

2011

Chen J

1.62(1.26, 2.08)

0.000

NA

 

GG vs. AG + AA

Total

 

1.38(0.46, 4.12)

0.564

0.000

  

2019

This study

0.51(0.31, 0.85)

0.009

NA

  

2017

Jia B

2.15(1.02, 4.52

0.043

NA

  

2011

Chen J

2.54(1.33, 8.45)

0.005

NA

 

GG + AG vs. AA

Total

 

1.25(0.77, 2.04)

0.373

0.012

  

2019

This study

0.75(0.48, 1.16)

0.195

NA

  

2017

Jia B

1.53(0.95, 2.45)

0.080

NA

  

2011

Chen J

1.65(1.21, 2.24)

0.001

NA

 

GG vs. AA

Total

 

1.50(0.45, 5.02)

0.513

0.000

  

2019

This study

0.49(0.27, 0.86)

0.014

NA

  

2017

Jia B

2.46(1.13, 5.35)

0.024

NA

  

2011

Chen J

2.95(1.53, 5.70)

0.001

NA

 

AG vs. AA

Total

 

1.28(1.01, 1.62)

0.120

0.241

  

2019

This study

0.91(0.57, 1.46)

0.705

NA

  

2017

Jia B

1.33(0.80, 2.20)

0.273

NA

  

2011

Chen J

1.49(1.08, 2.06)

0.016

NA

  1. Bold values are statistically significant of total values (P < 0.05).