Figure 1 | Scientific Reports

Figure 1

From: Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma

Figure 1

Expression of LAT1 in BC tissue and cells and functional significance of LAT1 in T24 and 5637 cells. LAT1 expression was detected in normal bladder tissue and bladder cancer tissue (A). LAT1 protein and mRNA levels were examined in T24, EJ-1, and 5637 cells (B). SiLAT1 significantly knocked down LAT1 expression in T24 and 5637 cells (C and D). SiLAT1 inhibited T24 and 5637 cell proliferation (E and F), migration (G and H), and invasion (I and J). Nega indicates negative siRNA control. Data represent three independent experiments with similar results. P-values were calculated by the Mann–Whitney U-test. *P < 0.05, **P < 0.01, ***P < 0.001.

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