Figure 5 | Scientific Reports

Figure 5

From: Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma

Figure 5

LAT1 and IGFBP-5 immunostaining and score distribution map of BC tissue immunostained for LAT1 and IGFBP-5. Representative images of LAT1 (A and C) and IGFBP-5 (B and D) IHC expression. Solid boxes indicate high magnification images of a high-grade cancer lesion (A and B). Dotted boxes indicate high magnification images of a low-grade cancer lesion (C and D). Distribution of the number of patients with LAT1 and IGFBP-5 expression (high/low) is indicated inside and outside the circle (E). The curve represents the progression-free survival of patients based on LAT1 expression (F) and LAT1 and IGFBP-5 expression (G). The curve represents the overall survival of patients based on LAT1 expression (H) and LAT1 and IGFBP-5 expression (I). P-values of the Kaplan–Meier survival analysis were calculated by the log-rank test. N.S., no significant difference. *P < 0.05, **P < 0.01, ***P < 0.001.

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