Table 1 Predictive factors of PFS.

From: Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma

 

Univariate Analysis

Multivariate Analysis

Cut off

HR

95% CI

P

HR

95% CI

P

Age

69

1.07

0.58–1.96

0.8327

   

Grade

3

6.03

2.19–24.96

0.0001

3.67

0.57–30.73

0.1719

pT stage

3

2.86

1.30–7.54

0.0073

0.81

0.21–3.80

0.7735

CRP (mg/dL)

0.60

1.19

0.64–2.26

0.5854

   

LDH (U/L)

201.00

2.45

1.23–4.96

0.0109

1.90

0.89–4.21

0.0965

ALT (IU/L)

9.00

1.01

0.55–1.91

0.9684

   

AST (IU/L)

17.00

0.94

1.51–1.75

0.8489

   

ALP (IU/L)

119.00

2.24

1.20–4.31

0.0109

2.97

1.32–6.89

0.0081*

Hb (g/dL)

9.90

1.08

0.58–2.04

0.8043

   

Alb (g/dL)

3.05

1.83

0.88–4.10

0.1093

   

NLR (ng/ml)

3.53

2.50

1.27–5.20

0.0079

1.16

0.48–3.06

0.7464

LAT1 score

1.14

3.14

1.70–5.98

0.0002

1.71

0.66–4.75

0.2702

IGFBP5 score

1.62

1.38

0.75–2.55

0.2966

   
  1. PFS = progression-free survival, HR = Cox proportional hazard ratio, 95% CI = 95% confidence interval, pT stage = pathological tumour stage, CRP = C-reactive protein, LDH = lactate dehydrogenase, ALT = alanine transaminase, AST = aminotransferase, ALP = alkaline phosphatase, Hb = haemoglobin, Alb = albumin, NLR = neutrophil-to-lymphocyte ratio. *means significant difference.
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