Table 4 Comparison of clinical factors between other and LAT1/IGFBP-5 high.

From: Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma

 

Other

LAT1/IGFBP-5 High

P

Age (years)

67.95 ± 8.13

69.04 ± 7.88

0.5899

Grade 3 or greater (%)

64.29

96.15

0.0026*

pT stage 3 or greater (%)

53.66

100.00

 < 0.0001*

CRP (mg/dL)

1.35 ± 2.38

188 ± 3.26

0.4584

LDH (U/L)

183.06 ± 50.23

219.91 ± 39.60

0.0064*

ALT (IU/L)

15.88 ± 27.45

9.41 ± 5.65

0.2796

AST (IU/L)

18.95 ± 14.21

17.50 ± 6.78

0.6523

ALP (IU/L)

134.93 ± 105.49

136.77 ± 47.43

0.9383

Hb (g/dL)

9.75 ± 1.72

10.10 ± 1.69

0.4259

Alb (U/L)

3.57 ± 1.28

3.31 ± 1.35

0.5007

NLR (ng/mL)

3.10 ± 1.49

4.43 ± 2.06

0.0070*

LAT1 staining score

0.66 ± 0.68

2.22 ± 0.40

 < 0.0001*

IGFBP-5 staining score

0.98 ± 0.82

2.40 ± 0.50

 < 0.0001*

  1. Data are expressed as mean ± standard deviation unless otherwise indicated. Other = low intensity of the LAT1 and IGFBP-5 immunoreaction and only low intensity of the LAT1 or IGFBP-5 immunoreaction, LAT1/IGFBP-5 High = high intensity of the LAT1 and IGFBP-5 immunoreaction, pT stage = pathological tumour stage, CRP = C-reactive protein, LDH = lactate dehydrogenase, ALT = alanine transaminase, AST = aminotransferase, ALP = alkaline phosphatase, Hb = haemoglobin, Alb = albumin, NLR = neutrophil-to-lymphocyte ratio. *means significant difference.
Back to article page