Figure 1 | Scientific Reports

Figure 1

From: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions

Figure 1

Proteomic analysis identifies oxidative protein modification in ectopic lesions. (A) Patient demographics and samples used in the proteomic analysis. (B) Example of peritoneal endometriotic lesions. The black filled arrows indicate blue lesions, the white filled arrows red lesions. Note the inflammation and fibrosis (transparent arrows). (C) Principal component analysis (PCA) separates endometriotic lesion from control tissue samples. The panel shows clustering of eutopic endometrium from control (blue) and endometriosis patients (magenta) against peritoneal lesions (yellow). (D) Oxidative protein modifications identified by MS in eutopic and ectopic samples. Modifications are grouped according to amino acid residue or N/K-linked formylation (M-methionine, D-aspartate, F-phenylalanine, K-lysine, N-asparagine, P-proline, R-arginine, Y-tyrosine, H-histidine, W-tryptophan and C-cysteine).

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