Figure 2 | Scientific Reports

Figure 2

From: Co-existence of PrPD types 1 and 2 in sporadic Creutzfeldt-Jakob disease of the VV subgroup: phenotypic and prion protein characteristics

Figure 2

Brain distribution of T1, including T120 and T121, and T2. (A,B) Quantitative distribution profiles of T1 and T2 in the indicated brain anatomical regions of -VV1 (A) and -VV2 (B). Each point of the profile is expressed as mean ± SEM; FC, TC, PC, EC, VC, OC: frontal, temporal, parietal, entorhinal, visual and occipital cortex; HI: hippocampus; BG: basal ganglia; TH: thalamus; SN: substantia nigra; CE: cerebellum. (C) Relative amounts of T1 and T2 in cerebral cortex (CC) and subcortical regions (Subcort.) of -VV1–2 mirrored those of -VV1 and -VV2, respectively; numbers under the ordinate indicate the percent amount of T2 implying that T1 accounts for remaining percentage (not shown); numbers embedded in the bar graphs indicate sample size. VV1 vs. VV2, P < 0.0003 (CC) and P < 0.0001 (Subcort.).

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