Table 4 Univariate and multivariate linear mixed model of factors associated with changes in average ganglion cell-inner plexiform layer thickness over time.
Univariate | p-value | Multivariate | p-value | |
|---|---|---|---|---|
Estimate (μm/year, 95% CI) | Estimate (μm/year, 95% CI) | |||
Age (years) | −0.155 (−0.247, −0.064) | 0.001 | −0.041 (−0.073, −0.007) | 0.019 |
Female sex | 0.799 (−1.199, 2.798) | 0.431 | ||
Duration of diabetes (years) | −0.628 (−0.829, −0.420) | 0.005 | −0.712 (−1.026, −0.254) | 0.016 |
HbA1c (%) | −0.618 (−1.423, 0.187) | 0.131 | ||
BCVA (logMAR) | −20.454 (−30.986, −9.921) | <0.001 | −2.550 (−6.541, 1.442) | 0.209 |
Intraocular pressure (mmHg) | 0.156 (−0.203, 0.514) | 0.367 | ||
Spherical equivalent (diopter) | −0.191 (−0.665, 0.284) | 0.429 | ||
Axial length (mm) | −0.682 (−2.065, 0.701) | 0.328 | ||
Baseline average GC-IPL (μm) | 0.854 (0.804, 0.904) | <0.001 | 0.830 (0.780, 0.881) | <0.001 |
