Table 1 SF-36 quality of life. GHQ (General Health Questionnaire) and GHQ with Likert scale results for the cohort studied, healthy contros (HC) and ME/CFS patients (N = 15/group).

From: Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

SF-36 Test

HC

ME/CFS

p value

Score

SD

Score

SD

Physical Functioning (PF)

56.8

2.0

21.6

3.0

1.29E-06

Role Physical (RP)

56.9

0.8

21.2

0.0

1.86E-07

Bodily Pain (BP)

56.9

5.0

32.4

12.2

3.69E-05

General Health (GH)

58.9

6.5

26.4

4.1

1.87E-14

Vitality (VT)

58.5

3.9

25.9

5.1

3.13E-06

Social Functioning (SF)

56.7

2.6

19.4

3.8

7.19E-07

Role Emotional (RE)

55.9

0.9

44.0

17.8

3.59E-03

Mental Health (MH)

55.1

2.6

45.4

11.9

1.44E-02

Physical Component Summary (PCS)

57.6

3.7

18.3

5.1

2.58E-08

Mental Health Component Summary (MCS)

55.6

2.2

43.3

12.7

4.06E-05

GHQ test

Score

SD

Score

SD

p value

scale A - Somatic Symptoms

0.3

0.8

3.7

2.9

5.28E-04

scale B - Anxiety and insomnia

0.1

0.3

1.6

2.3

5.22E-03

scale C - Social dysfunction

0.0

0.0

2.9

2.9

7.96E-05

scale D - Severe depression

0.0

0.0

0.8

1.4

1.80E-02

summary

0.3

0.8

9.1

8.1

2.31E-04

GHQ test with Likert scale

Score

SD

Score

SD

p value

scale A - Somatic Symptoms

2.8

1.9

12.5

5.8

1.16E-05

scale B - Anxiety and insomnia

3.1

2.1

6.5

5.4

6.66E-02

scale C - Social dysfunction

6.5

0.3

11.1

5.9

5.61E-03

scale D - Severe depression

0.0

0.3

2.7

4.2

2.10E-02

summary

12.5

3.2

32.8

19.1

3.64E-04

  1. Mean scores, standard deviations (SD) and p values are shown.