Table 3 Uni and multivariate linear regression model for serum and salivary ET-1 levels in all enrolled subjects. Age was included as continuous variable. For periodontitis and CHD, controls served as reference. For gender, male served as reference. For education, primary school served as a reference.

From: Analysis of Endothelin-1 Concentrations in Individuals with Periodontitis

Serum ET-1 levels

Univariate

Multivariate

Variable

B

95% CI

P

B

95% CI

P

CHD

0.377

0.216; 0.447

<0.001

0.064

−0.299; 0.475

0.684

   Periodontitis

0.222

0.011; 0.397

0.029

0.123

−0.049; 0.413

0.177

   hs-CRP

0.139

0.059; 0.112

<0.001

0.211

0.087; 0.117

<0.001

   Age (years)

−0.011

−0.341; 0.012

0.087

−0.045

−0.125; 0.236

0.411

   Female gender

0.133

−0.055; 0.412

0.185

0.147

−0.97; 0.412

0.057

   Education SES

−0.079

−0.187; 0.064

0.312

−0.078

−0.312; 0.478

0.254

Salivary ET-1 levels

   CHD

0.211

0.136; 0.654

<0.001

−0.058

−0.541; 0.313

0.549

   Periodontitis

0.055

−0.087; 0.331

0.378

0.008

−0.184; 0.168

0.784

   hs-CRP

0.074

0.038; 0.223

<0.001

0.074

0.038; 0.145

<0.001

   Age (years)

−0.041

−0.031; 0.009

0.201

0.005

−0.045; 0.036

0.841

   Female gender

0.055

−0.145; 0.236

0.491

0.079

−0.044; 0.315

0.231

   Total Cholesterol

−0.079

−0.174; −0.012

0.042

−0.87

−0.058; 0.239

0.043

   Serum ET-1

0.139

−0.035; 0.413

0.077

−0.028

−0.312; 0.174

0.553