Table 1 Baseline characteristics of the study subjects.

From: Statin treatment can reduce incidence of early seizure in acute ischemic stroke: A propensity score analysis

 

ES group (n = 66)

Non-ES group (n = 2903)

P value

Background

   

  Age, years

78.4 ± 9.8

74.1 ± 12.4

0.005

  Sex, male

36 (55)

1789 (62)

0.252

  Body mass index, kg/m2

20.8 ± 3.7

22.5 ± 3.8

<0.001

  Pre-morbid mRS, point

2.5 [0–4]

0 [0–2]

<0.001

  Hypertension

46 (70)

2279 (79)

0.096

  Dyslipidemia

24 (36)

1536 (53)

0.009

  Diabetes mellitus

19 (29)

735 (25)

0.567

  Atrial fibrillation

21 (32)

810 (28)

0.489

  Past history of stroke

27 (41)

902 (31)

0.106

  Congestive heart failure

12 (18)

349 (12)

0.129

  Current smoking

9 (14)

551 (19)

0.220

  Current alcohol consumption

13 (20)

1146 (39)

<0.001

Laboratory data

   

  LDL-cholesterol, mg/dl

106.9 ± 38.6

114.9 ± 35.3

0.069

  HDL-cholesterol, mg/dl

50.4 ± 14.4

50.5 ± 14.2

0.933

  Total-cholesterol, mg/dl

181.9 ± 43.7

190.3 ± 41.1

0.100

  Fasting plasma glucose, mg/dl

147.6 ± 70.5

136.1 ± 51.6

0.076

  BUN, mg/dl

19.8 ± 7.8

18.7 ± 9.0

0.324

  Creatinine, mg/dl

1.2 ± 1.0

1.1 ± 1.0

0.409

  C-reactive protein, mg/dl

1.4 ± 3.8

0.7 ± 2.1

0.018

  White blood cell count, x103/μl

8.3 ± 4.0

7.2 ± 2.6

<0.001

Clinical characteristics

   

  Systolic blood pressure, mm Hg

153.3 ± 32.6

160.9 ± 38.1

0.109

  Diastolic blood pressure, mm Hg

88.1 ± 24.6

85.5 ± 20.0

0.396

  Initial NIHSS, point

12.5 [5–25.3]

4 [2–11]

<0.001

  NIHSS severity

  

<0.001

  1, NIHSS ≤ 8

24 (36)

2043 (70)

 

  2, 9 ≤ NIHSS ≤ 15

15 (23)

296 (10)

 

  3, 16 ≤ NIHSS

27 (41)

591 (19)

 

Classification of subtype of AIS (TOAST)

  

<0.001

  Small-vessel occlusion

1 (1.5)

746 (26)

<0.001

  Large-artery atherosclerosis

12 (18)

453 (16)

0.606

  Cardioembolism

32 (49)

970 (33)

0.012

Imaging characteristics

   

  DWI-ASPECTS, point

10 [7–10]

10 [9,10]

0.055

  Hemorrhagic stroke

10 (15)

461 (16)

1.000

  Symptomatic hemorrhagic stroke

1 (1.5)

51 (1.8)

1.000

  Cortical stroke lesion

59 (89)

1598 (55)

<0.001

  Cortical stroke lesion in the MCA territory

54 (82)

1321 (46)

<0.001

  Cortical stroke lesion in the ACA territory

12 (18)

293 (10)

0.040

  Cortical stroke lesion in the PCA territory

10 (15)

334 (11)

0.333

  Large vessel occlusion or stenosis

33 (50)

1458 (50)

1.000

  Large vessel occlusion

27 (38)

930 (32)

0.309

  Large vessel stenosis

8 (11)

629 (22)

0.029

  1. Data are presented as mean ± standard deviation, median [interquartile range] or absolute (percentage) values. ES, early seizure; mRS, modified Rankin Scale; LDL, low-density cholesterol; HDL, high-density cholesterol; BUN, blood urea nitrogen; NIHSS, National Institutes of Health Stroke Scale; AIS, acute ischemic stroke; TOAST, Trial of Org 10172 in Acute Stroke Treatment; DWI-ASPECTS, Alberata Stroke Program Early CT Stroke score for MRI; MCA, middle cerebral artery; ACA, anterior cerebral artery; PCA, posterior cerebral artery.
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