Table 2 Incidence rate and adjusted hazard ratio of clinical outcomes in entire population.

From: Comparative Efficacy of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers after Coronary Artery Bypass Grafting

N, (%)

ARB group (N = 298)

ACEI group (N = 900)

Hazard Ratio (95% CI)

p-value

4-year follow up

  MACCE

29 (9.7)

101 (11.2)

0.69 (0.44–1.06)

0.09

  Total death

12 (4.0)

26 (2.9)

0.57 (0.25–1.30)

0.71

  Cardiac death

4 (1.3)

8 (0.9)

1.48 (0.39–5.73)

0.57

  MI

5 (1.7)

12 (1.3)

0.80 (0.26–2.50)

0.7

  Re-revascularization

7 (2.3)

37 (4.1)

1.15 (0.54–2.46)

0.18

  Stroke

10 (3.4)

38 (4.2)

0.57 (0.28–1.19)

0.14

  Heart failure

156 (52.3)

384 (42.7)

0.80 (0.26–2.50)

0.11

  Graft failure

7 (2.3)

28 (3.1)

0.57 (0.25–1.30)

0.92

1-year follow up

  MACCE

13 (4.4)

73 (8.1)

0.49 (0.27–0.91)

0.02

  Total death

4 (1.3)

9 (1.0)

1.42 (0.38–5.33)

0.6

  Cardiac death

3 (1.0)

3 (0.3)

5.55 (0.75–41.0)

0.09

  MI

1 (0.3)

8 (0.9)

0.29 (0.03–2.52)

0.26

  Re-revascularization

3 (1.0)

28 (3.1)

0.36 (0.11–0.20)

0.1

  Stroke

5 (1.7)

32 (3.6)

0.41 (0.15–1.07)

0.07

  Heart failure

3 (1.0)

1 (0.1)

32.43 (0.94–1122.4)

0.05

  Graft failure

7 (2.3)

17 (1.9)

1.61 (0.64–4.04)

0.31

  1. Values are N (%).
  2. ARB, Angiotensin receptor blocker; ACEi, Angiotensin converting enzyme inhibitor; CI, Confidence interval; MACCE, Major adverse cardiovascular and cerebrovascular events and composite of total death, cardiac death, myocardial infarction, re-revascularization and stroke; MI, Myocardial infarction.
  3. Cox hazard model regression analysis was adjusted for Age, Sex, diabetes mellitus, hypertension, left ventricular ejection fraction <40%, chronic renal failure, peripheral artery disease, old myocardial infarction, beta-blocker therapy, off-pump coronary artery bypass grafting.