Figure 3 | Scientific Reports

Figure 3

From: World Trade Center-Cardiorespiratory and Vascular Dysfunction: Assessing the Phenotype and Metabolome of a Murine Particulate Matter Exposure Model

Figure 3

LV Echo measures after 24-hrs: (A) Stroke volume (p = 0.034, n = 8) (B). Cardiac output (p = 0.030, n = 8), and at 1-M: (C). Heart rate (p = 0. 0.244, n = 8) (D). Cardiac output (p = 0.004, n = 8). Aortic Echo Measures after 24-hrs: (E). AET (P = 0.017, n = 6), (F). AAT/AET ratio (p = 0.007, n = 6), (G). Aortic VTI (P = 0.041, n = 6). (H,H’) LV in M-mode (representative images) for PM and PBS exposed after 1-M, respectively. Aortic measures after 1-M: (I) Aortic peak velocity (p = 0.022, n = 6), (J). AAT (p = 0.004, n = 6), (K). AET (p = 0.0163, n = 6), (L) AAT/AET (p = 0.004, n = 6), (M) VTI (p = 0.030, n = 6) and (N) Internal diameter (P = 0.565, n = 5). Aortic Imaging (representative) (O). Root diameter (B-mode) (P). Root Diameter (M-mode) (Q). Aortic flow (Doppler mode) 1-M after PM exposure in comparison to PBS; (O’,P’,Q’), respectively. *p < 0.05, **p < 0.01, ****p < 0.0001.

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