Figure 2 | Scientific Reports

Figure 2

From: COMT-Polymorphisms Modulated Functional Profile of the Fusiform Face Area Contributes to Face-Specific Recognition Ability

Figure 2

Comparisons of the group-mean PLS1 rFFA-MRI and PLS1 lFFA-MRI scores among three COMT haplotype groups. The difference in the PLS1 FFA-MRI scores was not significant between the hemispheres. Participants with the heterozygous-HEA COMT haplotype (intermediate dopamine availability) showed increased face selectivity (FS) and decreased fALFF (positive PLS1 FFA-MRI scores), whereas participants with the COMT homozygous HEA haplotype (high DA degrading enzymatic activity: a low level of DA) and HEA non-carriers (low DA degrading enzymatic activity: a high level of DA) showed decreased FS and increased rFFA-fALFF (negative FFA scores of PLS1). Error bars indicate the standard errors of the mean. *p < 0.05, **p < 0.01 (two-tailed).

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