Table 1 Baseline characteristics of the CHC patients before anti-HCV treatment.

From: Hepatitis C Virus Clearance with Glucose Improvement and Factors Affecting the Glucose Control in Chronic Hepatitis C Patients

Parameters

All patients

(N = 1090)

SVR(+)

(N = 990)

SVR(−)

(N = 100)

P-valuea

SVR(+) vs. SVR(−)

Male

490(45%)

44(44.9%)

45(45%)

0.992

Age, years

48(40–57)

48(40–57)

49(40–56)

0.993

Genotype

    

1

718(65.9%)

650(65.7%)

68(68%)

0.610

2

50(4.6%)

48(4.8%)

2(2%)

 

3

84(7.7%)

77(7.8%)

7(7%)

 

Others and unknown

238(21.8%)

215(21.7%)

23(23%)

 

HCV-RNA, log IU/mL

6.06(5.10–6.55)

6.05(5.11–6.54)

6.20(4.64–6.66)

0.419

FPG, mmol/L

5.31(4.94–5.85)

5.31(4.93–5.85)

5.34(5.02–5.83)

0.364

Prediabetes

278(25.5%)

250(25.2%)

28(28%)

0.537

Diabetes

89(8.16%)

82(8.28%)

7(7%)

 

TBiL, μmol/L

15.2(11.5–20.6)

15.2(11.5–20.5)

15.6(10.92–21.4)

0.822

ALT, IU/L

49(26–98)

49(26–99)

47(27–84)

0.594

AST, IU/L

45(30–78)

46(46–79)

42(30–76.75)

0.867

ALB, g/L

44(41.1–46.5)

44.1(41.2–46.6)

43.25(40.80–45.47)

0.038b

ALP, IU/L

82(68–106)

82(67–106)

86.50(71–105.75)

0.218

GGT, IU/L

34.50(19–76)

34(19–73.25)

39.5(39.5–81.75)

0.301

Hb, g/L

136(123–150)

137(123.75–150)

131.5(111.5–142)

0.003b

PLTs, 109/L

121(85–165)

123(86–166)

111(72.25–156.50)

0.147

WBCs, 109/L

5.02(3.91–6.35)

5.07(3.98–6.42)

4.34(4.34–5.655)

<0.001b

APRI

0.99(0.54–1.99)

0.98(0.54–1.98)

1.17(0.55–2.21)

0.522

FIB-4

2.63(1.49–5.09)

2.61(1.47–5.08)

2.69(1.73–5.28)

0.315

  1. CHC, chronic hepatitis C; HCV, Hepatitis C virus; SVR, sustained virologic response; HCV RNA, hepatitis C virus ribonucleic acid; FPG, fasting plasma glucose; TBiL, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALB, albumin; ALP, alkaline phosphatase; GGT, gamma glutamyltranspeptidase; Hb, hemoglobin; PLTs, platelets; WBCs, white blood cells; APRI, aspartate aminotransferase to platelet ratio index; FIB-4, Fibrosis-4. aThe χ2 test or Fisher’s exact probability test was used to examine the categorical variables such as sex, age genotype and diabetes status, and the Mann-Whitney U test was used to examine the continuous variables between SVR (+) and SVR (−) group. bValues were statistically significant at P < 0.05.