Figure 2
From: Context-Dependent Role of Vinculin in Neutrophil Adhesion, Motility and Trafficking
Vinculin plays a role in β2 integrin-dependent neutrophil motility. (a–d) Parameters of neutrophil motility during 30-minute chemokinesis on immobilized ICAM-1 and CXCL1 (n > 160 cells/group, 3 independent experiments). Analyzed using unpaired Student’s t-test. **p < 0.01; ***p < 0.001. (e) Mean-squared displacement of neutrophil migration based on particle modeling. Analyzed using linear regression with comparison of slopes. WT: y = 120t − 1338; VclKO: y = 60.5t − 431.3. ***p < 0.001. (f) Individual neutrophil tracks during 30-minute chemokinesis on immobilized ICAM-1 and CXCL1.
