Table 1 Clinical characteristics of patients with advanced lung adenocarcinoma eligible for further analysis.

From: Association of Divergent Carcinoembryonic Antigen Patterns and Lung Cancer Progression

Variable

With available data on EGFR mutation (n = 517)

With available data on CEAPd (n = 288)

Age (years)*

66 [59, 77]

64.5 [58, 73.8]

Age

<65 years

231 (44.7%)

144 (50.0%)

≥65 years

286 (55.3%)

144 (50.0%)

Sex

Female

275 (53.2%)

165 (57.3%)

Male

242 (46.8%)

123 (42.7%)

Stage

IIIB

84 (16.2%)

47 (16.3%)

IV

433 (83.8%)

241 (83.7%)

Smoking

Never

336 (65.0%)

198 (68.8%)

Ever

181 (35.0%)

90 (31.3%)

EGFR

Wild-type

190 (36.8%)

94 (32.6%)

Mutant

327 (63.2%)

194 (67.4%)

CEAIn

<5 ng/mL

199 (38.5%)

96 (33.3%)

5–100 ng/mL

215 (41.6%)

134 (46.5%)

>100 ng/mL

103 (19.9%)

58 (20.1%)

CEAPd

<5 ng/mL

NA

92 (31.9%)

5–100 ng/mL

NA

126 (43.8%)

>100 ng/mL

NA

70 (24.3%)

Follow-up Months*

15.4 [8.3, 25.5]

20.8 [13, 32.8]

  1. EGFR, epidermal growth factor receptor; CEAIn, serum CEA level at initial diagnosis; CEAPd, serum CEA level at disease progression; NA, not applicable.
  2. *Data were presented as median [25th and 75th percentiles].