Figure 5
From: Quantifying residue-specific conformational dynamics of a highly reactive 29-mer peptide
Reaction is accompanied by a significant drop in diffusional activation energy. Activation energy (Q) of rotational diffusion vs. TOAC position in unreacted (black) and reacted (red) MP01. Average Q (8.0 kBT unreacted, 3.4 kBT reacted) is plotted as a line. Notably, Q is relatively independent of residue number but drops by >60% upon conjugation. Due to the high error associated with MP01-J29, arising from low spectral intensity, Q is not provided for this peptide.
