Figure 7

Families of normalized current traces obtained from the double pulse protocol in response to caffeine challenge at a concentration of 2 mM in the absence (A,B) or the presence (C,D) of 10 μM dantrolene. (A,C) Control traces obtained in KH solution, prior to caffeine challenge. (B,D) Families of records obtained at successive (i) 3 or 5 min, (ii) 19 or 21 min and (iii) 29 or 31 min after addition of 2 mM caffeine-containing KH solution into the bath in (B) the absence or (D) presence of dantrolene.