Figure 5
From: Regulation of bone metabolism by megakaryocytes in a paracrine manner
Micro-computed tomography analyses of the femurs in ovariectomized C57B/L6 mice. Female C57B/L6 mice were ovariectomized at 9 weeks of age (n = 8 in each group), and conditioned media (CM) of megakaryocytes (MK) or pro-megakaryocytes (pro-MK) were injected via the tail vein once a day starting at 13 weeks of age for 4 weeks. Mice were then sacrificed for analyses at 17 weeks of age. (a) Body weight before (Pre) and after (Post) the injections. (b) Trabecular bone parameters of the femurs were also measured. BV/TV, bone volume per tissue volume; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular separation. Data are presented as mean ± SEM. NS, not significant.
