Table 2 Liver function markers and cholesterol level in the sera of rats in all the studied groups.

From: Vitis vinifera polyphenols from seedless black fruit act synergistically to suppress hepatotoxicity by targeting necroptosis and pro-fibrotic mediators

Groups

Albumin (g/dL)

ALT (IU/mL)

AST (IU/mL)

Cholesterol (mg/dL)

C

4.272 ± 0.166

43.167 ± 6.641

872.000 + 69.637

23.455 ± 2.052

V

3.742 ± 0.281

64.556 + 3.731

847.290 ± 94.022

13.098 ± 2.510

CCl4

2.926 ± 0.180**

27.700 ± 0.583

808.140 ± 96.285

*51.832 ± 15.89

CCl4-VVF1

4.492 ± 0.406

50.538 ± 0.700

842.733 ± 60.505

35.776 ± 2.863

CCl4-SM

3.222 ± 0.194

1.8336 ± 4.879

862.333 ± 157.410

26.701 ± 7.617

VVF1

4.077 ± 0.277

44.214 ± 1.364

832.551 ± 48.791

20.535 ± 5.368

SM

3.930 ± 0.256

44.901 ± 2.227

689.182 ± 53.572

8.289 ± 1.569

  1. Results are presented as Mean ± SE (n = 7). CCl4-VVF1 was compared with C, CCl4, V, and CCl4-SM while VVF1 was compared with C and SM. These comparisons were considered significantly different at *p < 0.05, **p < 0.005, ***p < 0.0005. ALT, alanine aminotransferase; AST, aspartate aminotransferase; SM, Silymarin; VVF1, Vitis vinifera fraction 1; V, vehicle.
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