Table 3 IC50 Values ( ± SEM) for chemical treatments in SOX17 differentiation assay.

From: Thalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4

hiPSC Line

XCL-1 hiPSC

Clone

CRBN Mock

CRBN KO/KI

SALL4 Mock

SALL4G416A

Thalidomide

1.9 ± 2.3

41 ± 37

1.8 ± 2.6

>50

Pomalidomide

0.02 ± 0.02

>50

0.01 ± 0.01

>50

Lenalidomide

33 ± 21

>50

44 ± 77

>50

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