Figure 1

Set up of the embedded multimodality imaging plateform. (A) Rationale for the selection of imaging modalities for each dedicated protocol. (B) Modified light enclosure dark box, door closed. (C) Door opened. (D) The first step is the BLI and NIRF configuration, with the camera, then the second step is US and PA configuration, with the ultrasound/photoacoustic transducer. (E) NIRF illumination device. The camera owns a lens with a filter holder in order to change emission filters allowing the assessment of fluorochromes with different emission spectra. The filtered fluorescence sources of light are positioned in six points around the lens (yellow arrows).