Figure 4
From: iLoF: An intelligent Lab on Fiber Approach for Human Cancer Single-Cell Type Identification
Description of transversal trapping forces exerted by the fabricated polymeric tip on Mock and HST6 tumoral cells and polystyrene particle. (A) Forces profile acting on each type of microparticle according to its position relatively to the trapping point (equilibrium position where each particle is stably trapped and the resultant of the forces acting on it is approximately null). The left part of the curves (corresponding to particle positions at the left of the equilibrium point) describe trapping forces profile when the particle is displaced towards the right (towards the +x direction) due to optical trapping. The right-hand side of the curves (corresponding to positions at the right of the trapping point) represent trapping forces exerted on the particle when it is moved towards −x direction (to the left). (B) Average maximum trapping forces exerted on Mock, HST6 cells and polystyrene particles, for left (blue) and right (orange) particle displacements due to optical trapping among the three displacements performed for each direction. (C) Comparison of forces exerted on Mock and HST6 cells considering distance points to trapping force normalized to the maximum displacement achieved by each cell due to optical trapping for one of the three displacements recorded for optical force analysis (\(P > \frac{0.05}{n},n=30\); Student T-test for independent samples with correction for multiple comparisons).
