Figure 2
From: Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes
Mouse model for gestational diabetes mellitus. Concentration of (A–C) plasma glucose and (D–I) insulin during a s.c. GTT. (A,D,G); lean mice (non-pregnant n = 62, pregnant n = 35), (B,E,H); oGDM mice (non-pregnant n = 25, pregnant n = 12), (C,F,I); oGH mice (non-pregnant n = 21, pregnant n = 10). (J) Body weight was assessed on the day of GTT. (K) Percentage of mice per cohort becoming pregnant after timed-mating. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 ((A–F) Two-way ANOVA followed by Sidak’s multiple comparison analysis, (G–I,K) Mann-Whitney U test, (J) Dunn’s Kruskal-Wallis multiple comparisons).
