Figure 5 | Scientific Reports

Figure 5

From: Single-cell Transcriptome Mapping Identifies Common and Cell-type Specific Genes Affected by Acute Delta9-tetrahydrocannabinol in Humans

Figure 5

THC receptor gene expression and co-expression network in B cells. (a) t-SNE plot showing THC receptor gene expression in distinct cell types of peripheral blood mononuclear cells. Small amount of CNR1 expression is observed in any of the cell types. CNR2 is highly expressed in B cells, followed by nature killer cells, CD8+ T-cells, and minimally expressed in CD4+ T-cells. GPR55 is highly expressed in CD4+ T-cells more than other cell types. GPR18 is widely expressed in peripheral blood mononuclear cells. (b) CNR2 expression is significantly correlated with 74 genes in B cells. The genes co-expressed with CNR2 are involved in functions of biological regulation, cellular process, immune system process, metabolic process, and signal functions.

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