Table 2 Statistics for models testing the differential relationship between acute BDNF change and pre-post change in trained task performance in the COG + PE and PE + COG groups.

From: Acute increases in brain-derived neurotrophic factor in plasma following physical exercise relates to subsequent learning in older adults

Factors

β

CI (95%)

df (num)

df (dn)

F

p

Trained tasks (untrained stimuli)

(Intercept)

   Group

−0.1662

−0.4702

0.1378

1

45.00

1.15

0.2896

   Time

0.3454

0.2430

0.4479

1

45.00

43.72

<0.0001

   BDNF

0.3297

0.0972

0.5622

1

45.00

7.73

0.0080

   Group × Time

10.0734

−0.1758

0.0290

1

45.00

1.97

0.1669

   Group × BDNF

0.0634

−0.2442

0.3709

1

45.00

0.16

0.6882

   Time × BDNF

0.0938

−0.0102

0.1977

1

45.00

3.13

0.0834

   Group × Time × BDNF

0.1441

0.04025

0.2480

1

45.00

7.39

0.0093

Trained tasks (trained stimuli)

(Intercept)

   Group

−0.0992

−0.3540

0.1558

1

45.00

0.58

0.4499

   Time

0.5000

0.3535

0.6459

1

45.00

44.88

<0.0001

   BDNF

0.2904

0.0954

0.4855

1

45.00

8.52

0.0055

   Group × Time

−0.0248

−0.1710

0.1214

1

45.00

0.11

0.7412

   Group × BDNF

−0.0482

−0.3062

0.2100

1

45.00

0.13

0.7161

   Time × BDNF

0.0944

−0.0539

0.2428

1

45.00

1.56

0.2187

   Group × Time × BDNF

0.0841

−0.0643

0.2325

1

45.00

1.23

0.2726

  1. Standardized parameter estimates from the linear mixed effects models and F-tests of main and interaction effects (Type III anova). For unstandardized parameter estimates (S11). P-values that are below the Bonferroni-corrected significance threshold are highlighted in bold (αcorr = 0.0125). Group = COG + PE < PE + COG; Time = pretest <posttest; BDNF = change in plasma BDNF concentration following PE at pretest.