Figure 7
From: CCN1 promotes hepatic steatosis and inflammation in non-alcoholic steatohepatitis
CCN1 exacerbates murine primary hepatocyte steatosis. (A) Oil red O-stained sections of primary hepatocytes treated with Ad-GFP or Ad-CCN1. (B) Statistical analysis of the TG concentration in murine primary hepatocytes treated with Ad-GFP or Ad-CCN1. (C) Oil red O-stained sections of primary hepatocytes treated with Ad-shGFP or Ad-shCCN1. (D) Statistical analysis of the TG concentration in murine primary hepatocytes treated with Ad-shGFP or Ad-shCCN1. (E) Expression of TNF-α was quantified in primary hepatocytes of Ad-GFP group and Ad-CCN1group. (F) Expression of MCP-1 was quantified in primary hepatocytes of Ad-GFP group and Ad-CCN1group. (G) Expression of IL-10 was quantified in primary hepatocytes of Ad-GFP group and Ad-CCN1 group. Statistical significance was assessed by two-tailed Student’s t test. The error bar indicates the SD. *P < 0.05; **P < 0.01; ns: no significance.
