Figure 5

Long-term alterations on kynurenine pathway generated by Pb2+ treatment during lactation period of mice. (A) KAT II activity, (B) KYNA levels, (C) KMO activity and (D) 3-HK levels were evaluated in hippocampus, striatum, cortex and cerebellum of mice at 60 PND. Data are mean ± S.E.M. *P < 0.01 vs. each respective brain region control, T-test and Mann-Whitney test. N = 8 per group.